Description

2-Oxo-5-(Trifluoromethyl)-1,2-Dihydropyridine-3-Carboxylic Acid is a high-value, multi-functional heterocyclic building block characterized by its pyridone core and trifluoromethyl group. This compound matters for its critical role in modern pharmaceutical and agrochemical research, where it serves as a versatile precursor for synthesizing novel active ingredients. Pharmaceutical R&D teams and fine chemical manufacturers need this intermediate to develop new drug candidates, particularly in therapeutic areas requiring the unique physicochemical properties imparted by the trifluoromethyl moiety.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science: Serves as a precursor for advanced organic materials, including liquid crystals and organic semiconductors, due to its rigid, planar structure.
• Chemical Synthesis: Acts as a versatile synthon in organic chemistry for constructing complex heterocyclic systems via condensation, cyclization, and cross-coupling reactions.
• Bioconjugation & Probe Development: The carboxylic acid functionality allows for derivatization and conjugation, making it useful in creating biochemical probes and diagnostic agents.

Basic Information

Product Name	2-Oxo-5-(Trifluoromethyl)-1,2-Dihydropyridine-3-Carboxylic Acid
CAS No.	787640-16-8
Molecular Formula	C7H4F3NO3
Molecular Weight	207.11 g/mol
Synonyms	5-(Trifluoromethyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 1,2-dihydro-5-(trifluoromethyl)-2-oxo-; 5-Trifluoromethyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid; 1,2-Dihydro-5-(trifluoromethyl)-2-oxo-3-pyridinecarboxylic acid; 2-Hydroxy-5-(trifluoromethyl)nicotinic acid; 2-Oxo-5-trifluoromethyl-1,2-dihydropyridine-3-carboxylic acid; 5-(Trifluoromethyl)-2-hydroxynicotinic acid
EINECS	Contact for details

Quality Control

Our 2-Oxo-5-(Trifluoromethyl)-1,2-Dihydropyridine-3-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and advanced chemical synthesis. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and compliance assurance for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.