Description

(R)-Phosphoric Acid Mono-[2-Amino-2-(6-Octyl-1H-Benzoimiazol-2-Yl)-Ethyl] Ester CAS NO 787582-98-3 is a chiral, organophosphorus compound featuring a benzimidazole core, designed for advanced pharmaceutical and biochemical research. This molecule is of significant interest due to its potential as a key synthetic intermediate or a pharmacologically active scaffold, particularly in the development of targeted therapeutics and enzyme inhibitors. It is primarily sought by research institutions and pharmaceutical companies engaged in drug discovery, asymmetric synthesis, and the development of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for kinase inhibitors or other targeted therapies.
• Biochemical Research: Used as a tool compound or a precursor in studying enzyme mechanisms, signal transduction pathways, and cellular processes.
• Asymmetric Catalysis: Potential application as a ligand or catalyst component in stereoselective synthesis due to its chiral phosphoric acid moiety.
• Medicinal Chemistry: Core structure for structure-activity relationship (SAR) studies aimed at optimizing potency, selectivity, and pharmacokinetic properties of drug candidates.
• Peptidomimetic Development: The amino acid-like structure makes it suitable for incorporation into peptidomimetics and other bioactive peptide analogs.
• High-Purity Reference Standard: Supplied as a certified reference material for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	(R)-Phosphoric Acid Mono-[2-Amino-2-(6-Octyl-1H-Benzoimiazol-2-Yl)-Ethyl] Ester
CAS No.	787582-98-3
Molecular Formula	C₁₇H₂₈N₃O₄P
Molecular Weight	369.40 g/mol
Synonyms	(R)-2-Amino-2-(6-octyl-1H-benzo[d]imidazol-2-yl)ethyl dihydrogen phosphate; (R)-Phosphorylethanolamine benzimidazole derivative; 2-Amino-2-(6-octyl-1H-benzimidazol-2-yl)ethyl phosphate (R-enantiomer); (R)-6-Octyl-1H-benzimidazol-2-yl)ethylphosphoramidate; (R)-HPAOBE; (R)-Benzimidazole phosphoamino acid ester; UNII-Contact for details; (R)-Mono(2-amino-2-(6-octyl-1H-benzoimidazol-2-yl)ethyl) phosphate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of (R)-Phosphoric Acid Mono-[2-Amino-2-(6-Octyl-1H-Benzoimiazol-2-Yl)-Ethyl] Ester is characterized and released against stringent specifications, with a focus on chiral purity, chemical identity, and impurity profile. Certificates of Analysis (COA) detailing results from HPLC, NMR, and optical rotation tests are available upon request. We adhere to cGMP guidelines for the production of materials intended for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.