Description

Piperidine, 3-Fluoro-, Hydrochloride (1:1), (3R)- is a high-purity, single-enantiomer chiral building block essential for advanced pharmaceutical and agrochemical research. This compound, with CAS number 787564-37-8, is a key intermediate in the synthesis of complex molecules, offering a defined stereocenter for creating targeted bioactive agents. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the specific stereochemistry influences biological activity.
• Asymmetric Catalysis: Serves as a precursor or ligand in catalytic systems for stereoselective chemical transformations.
• Medicinal Chemistry Research: Employed in hit-to-lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Process Chemistry: Used in scaling up synthetic routes for kilogram-scale production under Good Manufacturing Practice (GMP) guidelines.
• Chemical Biology: Acts as a molecular probe or scaffold for studying enzyme interactions and biological pathways.

Basic Information

Product Name	Piperidine, 3-Fluoro-, Hydrochloride (1:1), (3R)-
CAS No.	787564-37-8
Molecular Formula	C5H11FN • HCl
Molecular Weight	139.61 (Free base) / 176.02 (Hydrochloride)
Synonyms	(R)-3-Fluoropiperidine Hydrochloride; (3R)-3-Fluoropiperidine Hydrochloride; (R)-3-Fluoro-piperidine HCl; 3-Fluoropiperidine Hydrochloride, (R)-; 3R-Fluoropiperidine HCl; (R)-3-Fluoropiperidinium Chloride; 3-Fluoro-(R)-piperidine hydrochloride; (R)-3-Fluoropiperidine Hydrochloride Salt
EINECS	Contact for details

Quality Control

Our Piperidine, 3-Fluoro-, Hydrochloride (1:1), (3R)- is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including chiral purity verification by HPLC. Certificates of Analysis (COA) detailing identity, assay, enantiomeric excess, and impurity profiles are available for every batch. Our quality commitment supports compliance with ISO standards and GMP guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.