Description

2-Pyridinecarboxylicacid,1,2,3,6-Tetrahydro-6-Methyl-,Methylester,trans- is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and production of novel therapeutic agents, including potential central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing chiral ligands used in asymmetric catalysis.
• Academic and R&D Laboratories: Employed in methodological studies and the discovery of new chemical entities (NCEs).
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	2-Pyridinecarboxylicacid,1,2,3,6-Tetrahydro-6-Methyl-,Methylester,trans-
CAS No.	787514-40-3
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	trans-6-Methyl-1,2,3,6-tetrahydropyridine-2-carboxylic acid methyl ester; Methyl (2R,6S)-6-methyl-1,2,3,6-tetrahydropyridine-2-carboxylate; Methyl trans-6-methyl-1,2,3,6-tetrahydropyridine-2-carboxylate; (2R,6S)-6-Methyl-1,2,3,6-tetrahydropyridine-2-carboxylic acid methyl ester; 1,2,3,6-Tetrahydro-6-methyl-2-pyridinecarboxylic acid methyl ester, trans-; trans-6-Methyl-2-methoxycarbonyl-1,2,3,6-tetrahydropyridine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We offer material produced under GMP-like conditions for pharmaceutical applications, with strict in-process controls. Certificates of Analysis (COA) are available upon request, detailing purity, chiral purity, and impurity profiles as determined by advanced analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.