Description

2-(3-Bromo-Phenyl)-Thiazole-4-Carboxylic Acid Ethyl Ester is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its functionalized thiazole and brominated phenyl rings, which serve as key intermediates for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, especially those targeting neurological disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a building block for organic semiconductors, liquid crystals, and advanced polymers due to its conjugated system.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Stille) where the bromo substituent acts as a handle for further functionalization.
• Ligand and Catalyst Development: Utilized in the creation of novel ligands for metal catalysis and organocatalysts.
• Academic & R&D: A valuable reagent for methodological studies and exploring new synthetic pathways in university and corporate laboratories.

Basic Information

Product Name	2-(3-Bromo-Phenyl)-Thiazole-4-Carboxylic Acid Ethyl Ester
CAS No.	786654-97-5
Molecular Formula	C12H10BrNO2S
Molecular Weight	312.18 g/mol
Synonyms	Ethyl 2-(3-bromophenyl)-1,3-thiazole-4-carboxylate; 2-(3-Bromophenyl)-4-(ethoxycarbonyl)thiazole; 4-Carbethoxy-2-(3-bromophenyl)thiazole; 2-(3-Bromophenyl)thiazole-4-carboxylic acid ethyl ester; 1,3-Thiazole-4-carboxylic acid, 2-(3-bromophenyl)-, ethyl ester; 3-Bromo-2-(4-(ethoxycarbonyl)thiazol-2-yl)benzene (tautomeric form); 786654-97-5
EINECS	Contact for details

Quality Control

Every batch of 2-(3-Bromo-Phenyl)-Thiazole-4-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are supplied with comprehensive analytical documentation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Assay	≥ 96.0% (by HPLC normalization)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.