Description

1-Pyrrolidineaceticacid,α-Methyl-,(Alphas)-(9Ci) is a specialized chiral intermediate of significant interest in advanced organic synthesis. Its pyrrolidine-acetic acid scaffold makes it a valuable building block for constructing complex molecules with defined stereochemistry. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, where precise molecular architecture is critical.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Asymmetric Synthesis: Utilized as a precursor or ligand in catalytic asymmetric reactions to induce chirality in target molecules.
• Fine Chemical Production: Serves as a building block for the synthesis of complex agrochemicals, flavors, and fragrances requiring specific stereoisomers.
• Academic & Industrial Research: Used in methodological studies and process chemistry development for constructing nitrogen-containing heterocycles.
• Ligand and Catalyst Development: Its structure can be modified to create novel ligands for metal-catalyzed transformations.

Basic Information

Product Name	1-Pyrrolidineaceticacid,α-Methyl-,(Alphas)-(9Ci)
CAS No.	786627-71-2
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	(αS)-α-Methyl-1-pyrrolidineacetic acid; (S)-2-(1-Pyrrolidinyl)propanoic acid; L-α-Methylproline; (S)-α-Methylproline; (S)-2-Pyrrolidin-1-ylpropanoic acid; 1-Pyrrolidinepropanoic acid, α-methyl-, (αS)-; (S)-1-(1-Carboxyethyl)pyrrolidine
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our chiral intermediates. Each batch of 1-Pyrrolidineaceticacid,α-Methyl-,(Alphas)-(9Ci) is characterized and tested to ensure identity, purity, and enantiomeric excess meet exacting standards. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay, chiral purity (HPLC), and residual solvents is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.