Description

2,2-Difluoropropyl Trifluoromethanesulfonate is a high-purity fluorinated sulfonate ester, a key building block in advanced organic synthesis. This compound is valued for its exceptional reactivity as a versatile alkylating and fluorinating agent, enabling the efficient introduction of difluoropropyl groups into complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing fluorine-containing motifs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides where fluorinated compounds offer improved efficacy and environmental profile.
• Ligand & Catalyst Preparation: Serves as a precursor for synthesizing specialized fluorinated ligands and organometallic catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science: Employed in the production of fluorinated polymers, liquid crystals, and electronic chemicals to impart unique thermal, chemical, and surface properties.
• Organic Methodology Development: A valuable tool for academic and industrial research in developing new fluorination and functionalization reactions.
• PET Tracer Precursor: Potential use in radiochemistry for synthesizing precursors to Positron Emission Tomography (PET) imaging agents.

Basic Information

Item	Detail
Product Name	2,2-Difluoropropyl Trifluoromethanesulfonate
CAS No.	784193-15-3
Molecular Formula	C4H5F5O3S
Molecular Weight	228.14 g/mol
Synonyms	2,2-Difluoropropyl Triflate; 1,1-Difluoropropan-2-yl Trifluoromethanesulfonate; 2,2-Difluoroprop-1-yl Triflate; Trifluoromethanesulfonic Acid 2,2-Difluoropropyl Ester; 2,2-Difluoropropyl Trifluoromethylsulfonate; (2,2-Difluoropropyl) Triflate; 2,2-Difluoropropyl Tosylate Analog (Fluorinated)
EINECS	Contact for details

Quality Control

Every batch of 2,2-Difluoropropyl Trifluoromethanesulfonate is manufactured and tested under strict quality management systems. We guarantee high chemical purity and consistency, supported by comprehensive analytical documentation. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles via NMR, HPLC, and GC analysis is provided with each shipment to ensure it meets your precise research and process requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.