Description

7-Azaspiro[3.5]Nonan-2-Ol is a high-purity, nitrogen-containing spirocyclic alcohol building block of significant interest in advanced organic synthesis. Its unique fused bicyclic structure makes it a valuable intermediate for constructing complex molecular architectures with potential biological activity. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization due to its rigid, three-dimensional spirocyclic scaffold.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides, fungicides, or insecticides with novel modes of action.
• Ligand and Catalyst Development: The nitrogen and oxygen functionalities make it a candidate for creating novel chiral ligands or organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological targets and pathways.
• Advanced Material Research: Investigated as a monomer or additive for specialty polymers with specific thermal or mechanical properties.

Basic Information

Item	Details
Product Name	7-Azaspiro[3.5]Nonan-2-Ol
CAS No.	784137-09-3
Molecular Formula	C8H15NO
Molecular Weight	141.21 g/mol
Synonyms	7-Azaspiro[3.5]nonan-2-ol; 2-Hydroxy-7-azaspiro[3.5]nonane; 7-Azaspiro[3.5]nonan-2-ol; Azaspirocyclic alcohol; 7-Aza-spiro[3.5]nonan-2-ol; 2-Azaspiro[4.4]nonan-8-ol (tautomeric form); Spirocyclic amino alcohol
EINECS	Contact for details

Quality Control

Every batch of 7-Azaspiro[3.5]Nonan-2-Ol is manufactured and tested under a strict quality management system. We ensure compliance with high-purity standards suitable for research and development applications. Comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, is performed to guarantee identity, potency, and purity. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (enantiomerically enriched)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.