Description

1-Piperidinecarboxylic Acid, 4-[(Z)-Amino(Hydroxyimino)Methyl]-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and functional groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting specific biological pathways. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, including enzyme inhibitors and receptor modulators.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly protease inhibitors and other enzyme-targeted therapies.
• Chemical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Peptidomimetic Synthesis: Serves as a crucial component for creating peptide-like molecules with enhanced stability and bioavailability.
• Bioconjugation: The reactive amino(hydroxyimino)methyl group enables its use in linking molecules for diagnostic or targeted drug delivery systems.
• Academic Research: Employed in university and institutional labs for studying biochemical pathways and developing new synthetic methodologies.

Basic Information

Product Name	1-Piperidinecarboxylic Acid, 4-[(Z)-Amino(Hydroxyimino)Methyl]-, 1,1-Dimethylethyl Ester
CAS No.	782493-60-1
Molecular Formula	C12H23N3O3
Molecular Weight	257.33 g/mol
Synonyms	tert-Butyl 4-[(Z)-amino(hydroxyimino)methyl]piperidine-1-carboxylate; 4-Carbamoyloximinomethyl-piperidine-1-carboxylic acid tert-butyl ester; 1-Boc-4-[(Z)-C-amidoximo]piperidine; 4-[(Z)-Amino(hydroxyimino)methyl]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1-N-Boc-4-amidinopiperidine oxime; Boc-4-amidinopiperidine oxime; (Z)-tert-Butyl 4-(amino(hydroxyimino)methyl)piperidine-1-carboxylate
EINECS	Contact for details

Quality Control

Our production of 1-Piperidinecarboxylic Acid, 4-[(Z)-Amino(Hydroxyimino)Methyl]-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity, correct stereochemistry (Z-isomer), and the absence of critical impurities. Certificates of Analysis (COA) detailing all specifications are available upon request. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isomeric Purity (Z-isomer, HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.