Description

2-Pyridinecarboxylicacid,1,2,3,6-Tetrahydro-4-Methyl-,Ethylester,(R)-(9Ci) is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound matters for its role as a key building block in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, where stereochemical purity is critical. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of novel APIs, particularly in central nervous system (CNS) and other therapeutic areas.
• Asymmetric Synthesis: Used as a starting material or ligand precursor in catalytic asymmetric reactions to induce chirality in target molecules.
• Agrochemical Research: Serves as a building block for the synthesis of advanced, enantiomerically pure pesticides and herbicides.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.
• Ligand and Catalyst Development: Used to synthesize novel chiral ligands for transition metal catalysis.

Basic Information

Item	Detail
Product Name	2-Pyridinecarboxylicacid,1,2,3,6-Tetrahydro-4-Methyl-,Ethylester,(R)-(9Ci)
CAS No.	782426-43-1
Molecular Formula	C10H15NO2
Molecular Weight	181.23 g/mol
Synonyms	(R)-1,2,3,6-Tetrahydro-4-methyl-2-pyridinecarboxylic acid ethyl ester; Ethyl (R)-1,2,3,6-tetrahydro-4-methylpicolinate; (R)-4-Methyl-1,2,3,6-tetrahydropyridine-2-carboxylic acid ethyl ester; (R)-Ethyl 4-methyl-3,6-dihydro-2H-pyridine-2-carboxylate; (R)-ETHP; (R)-Enantiomer of Tebanicline intermediate; Chiral nipecotic acid derivative
EINECS	Contact for details

Quality Control

Our 2-Pyridinecarboxylicacid,1,2,3,6-Tetrahydro-4-Methyl-,Ethylester,(R)-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure compliance with exacting research and pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.