Description

1-Piperidinecarboxylic Acid, 4-[(2-Amino-3-Pyridinyl)Amino]-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate of significant importance in modern drug discovery and development. Its core value lies in its role as a key building block for synthesizing complex, biologically active molecules, particularly kinase inhibitors and other targeted therapeutics. This compound is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of novel small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitor candidates.
• Oncology Research: Used in the research and development of targeted cancer therapies due to its specific molecular scaffold.
• Medicinal Chemistry: Serves as a versatile building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot and commercial manufacturing scales.
• Biochemical Research: May be used as a tool compound or ligand in biochemical assays to study specific enzyme interactions.
• Custom Synthesis: A starting material for the contract synthesis of more complex, proprietary molecules for clients.

Basic Information

Product Name	1-Piperidinecarboxylic Acid, 4-[(2-Amino-3-Pyridinyl)Amino]-, 1,1-Dimethylethyl Ester
CAS No.	781649-86-3
Molecular Formula	C15H24N4O2
Molecular Weight	292.38 g/mol
Synonyms	tert-Butyl 4-[(2-amino-3-pyridinyl)amino]piperidine-1-carboxylate; 4-[(2-Amino-3-pyridinyl)amino]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1-Boc-4-[(2-amino-3-pyridinyl)amino]piperidine; 4-(2-Amino-3-pyridinylamino)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(2-amino-3-pyridinylamino)piperidine-1-carboxylate; 781649-86-3; 4-[(2-Aminopyridin-3-yl)amino]piperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 1-Piperidinecarboxylic Acid, 4-[(2-Amino-3-Pyridinyl)Amino]-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.