Description

2-Oxo-1-(4-Piperidinyl)-2,3-Dihydro-1H-Imidazo[4,5-B]Pyridine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate of significant interest in modern drug discovery. This compound serves as a critical building block for the synthesis of novel therapeutic agents, particularly in the development of kinase inhibitors and other targeted small molecule drugs. It is essential for research and development laboratories, contract manufacturing organizations (CMOs), and pharmaceutical companies engaged in the creation of new chemical entities (NCEs) for oncology, neurology, and inflammatory diseases.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potent kinase inhibitors and other biologically active molecules.
• Drug Discovery Research: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold in the development of new APIs for clinical trials.
• Contract Synthesis: Supplied to CROs and CMOs for custom synthesis projects requiring high-fidelity chemical building blocks.
• Biochemical Research: Employed as a tool compound in biochemical assays to study specific enzyme interactions and pathways.

Basic Information

Product Name	2-Oxo-1-(4-Piperidinyl)-2,3-Dihydro-1H-Imidazo[4,5-B]Pyridine Dihydrochloride
CAS No.	781649-84-1
Molecular Formula	C11H14N4O · 2HCl
Molecular Weight	303.18 g/mol
Synonyms	1-(Piperidin-4-yl)-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one dihydrochloride; 1-(4-Piperidinyl)-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one hydrochloride (1:2); 781649-84-1; UNII-9G4J2F8Y0F; 9G4J2F8Y0F; 2-Oxo-1-(4-piperidinyl)-2,3-dihydro-1H-imidazo[4,5-b]pyridine dihydrochloride; 1-(Piperidin-4-yl)-2,3-dihydro-1H-imidazo[4,5-b]pyridin-2-one dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-Oxo-1-(4-Piperidinyl)-2,3-Dihydro-1H-Imidazo[4,5-B]Pyridine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.