Description

Spiro[5.5]Undec-1-En-3-One, 8-Methylene- (9Ci) is a specialized spirocyclic ketone building block of significant interest in advanced organic synthesis. This compound matters for its unique bridged, rigid molecular framework, which is highly valuable for constructing complex three-dimensional structures in medicinal chemistry and materials science. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fragrance industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly those requiring complex, sterically defined architectures.
• Agrochemical Research: Used in the development of new pesticides and herbicides where the spirocyclic core can impart specific biological activity and stability.
• Fragrance & Flavor Chemistry: Serves as a precursor for unique musk-like or woody odorants due to its complex hydrocarbon skeleton.
• Material Science: Investigated as a monomer or cross-linking agent for creating polymers with tailored thermal and mechanical properties.
• Academic & R&D: A valuable tool for methodological studies in organic synthesis, including cycloaddition and ring-expansion reactions.
• Catalyst & Ligand Development: The rigid backbone can be functionalized to create novel chiral ligands or organocatalysts.

Basic Information

Product Name	Spiro[5.5]Undec-1-En-3-One, 8-Methylene- (9Ci)
CAS No.	780789-87-9
Molecular Formula	C12H16O
Molecular Weight	176.26 g/mol
Synonyms	8-Methylenespiro[5.5]undec-1-en-3-one; 8-Methylenespiro[5.5]undec-1-en-3-one (9CI); Spiro[5.5]undec-1-en-3-one, 8-methylene-; 780789-87-9; 8-Methylenespiro[5.5]undec-1-en-3-one; 8-Methylene-spiro[5.5]undec-1-en-3-one
EINECS	Contact for details

Quality Control

Our Spiro[5.5]Undec-1-En-3-One, 8-Methylene- (9Ci) is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (by HPLC or GC), identity (by IR, NMR), and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.