Description

Bicyclo[2.2.1]Heptane-2-Acetic Acid, 5-Methylene-, Ethyl Ester, (1R,2R,4R)-Rel- (9Ci) is a high-purity, stereochemically defined bicyclic compound that serves as a critical chiral building block and advanced intermediate in sophisticated organic synthesis. Its rigid, functionalized norbornane-like structure makes it invaluable for constructing complex molecular architectures with precise three-dimensional control. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-fidelity intermediates for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its bicyclic framework contributes to unique biological activity and environmental stability.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers, resins, and liquid crystals with tailored thermal and mechanical properties.
• Asymmetric Catalysis Ligand Synthesis: The defined stereocenters and rigid backbone make it a valuable starting material for constructing novel chiral ligands and organocatalysts.
• Fragrance & Flavor Chemistry: Used as an intermediate for creating complex, proprietary odorants and flavor molecules with unique olfactory profiles.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis, including studies on cycloaddition reactions and stereoselective transformations.

Basic Information

Product Name	Bicyclo[2.2.1]Heptane-2-Acetic Acid, 5-Methylene-, Ethyl Ester, (1R,2R,4R)-Rel- (9Ci)
CAS No.	780789-84-6
Molecular Formula	C₁₂H₁₈O₂
Molecular Weight	194.27 g/mol
Synonyms	rel-(1R,2R,4R)-5-Methylenenorbornane-2-acetic acid ethyl ester; Ethyl 5-methylenenorbornane-2-acetate; (1R,2R,4R)-rel-5-Methylenebicyclo[2.2.1]heptane-2-acetic acid ethyl ester; Bicyclo[2.2.1]heptane-2-acetic acid, 5-methylene-, ethyl ester, (1R,2R,4R)-rel-; 5-Methylenenorborn-2-ylacetic acid ethyl ester; Ethyl (1R,2R,4R)-rel-5-methylenenorbornane-2-acetate
EINECS	Contact for details

Quality Control

Every batch of Bicyclo[2.2.1]Heptane-2-Acetic Acid, 5-Methylene-, Ethyl Ester, (1R,2R,4R)-Rel- (9Ci) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC and GC/MS, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources, strong oxidizing agents, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.