Description

2,2-Difluoro-2-(5-Methylpyridin-2-Yl)Ethanol is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a difluoroethanol moiety and a methylpyridine ring, makes it an essential intermediate for creating novel compounds with tailored properties. This product is primarily required by pharmaceutical and agrochemical R&D sectors for the development of new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and insecticides, where the fluorine atoms and heterocyclic structure can enhance biological activity and environmental stability.
• Ligand & Catalyst Precursor: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the creation of novel fluorinated polymers and liquid crystals, where it can impart unique solubility and electronic characteristics.
• Chemical Biology Probes: Utilized as a core structure for developing molecular probes and tags used in bioimaging and diagnostic assay development.

Basic Information

Product Name	2,2-Difluoro-2-(5-Methylpyridin-2-Yl)Ethanol
CAS No.	780769-39-3
Molecular Formula	C8H9F2NO
Molecular Weight	173.16 g/mol
Synonyms	2-(5-Methylpyridin-2-yl)-2,2-difluoroethanol; 2,2-Difluoro-2-(5-methyl-2-pyridinyl)ethanol; 2-(5-Methyl-2-pyridyl)-2,2-difluoroethanol; 5-Methyl-2-(2,2-difluoro-2-hydroxyethyl)pyridine; 2,2-Difluoro-1-(5-methylpyridin-2-yl)ethanol; 1-(5-Methylpyridin-2-yl)-2,2-difluoroethan-1-ol
EINECS	Contact for details

Quality Control

Our 2,2-Difluoro-2-(5-Methylpyridin-2-Yl)Ethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Custom synthesis and purity grades (e.g., >98%, >99%) are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its chemical nature, keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.