Description

4-Pentenoicacid,2-Amino-5-Cyano-,Methylester,[S-(Z)]-(9Ci) is a specialized chiral building block with significant synthetic utility. This compound matters for its role as a key intermediate in the synthesis of complex, biologically active molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel compounds and developing new synthetic routes.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of potential active pharmaceutical ingredients (APIs), especially those containing amino acid and cyano functionalities.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides where its specific stereochemistry and functional groups are essential for bioactivity.
• Peptidomimetics & Drug Discovery: Serves as a constrained scaffold for creating peptide analogs and other drug-like molecules in medicinal chemistry programs.
• Asymmetric Synthesis: Employed as a starting material or intermediate in catalytic asymmetric reactions to introduce chirality into target molecules.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing high-value, complex organic compounds.
• Academic & Industrial R&D: A valuable reagent for methodological studies and exploring new chemical spaces in university and corporate research laboratories.

Basic Information

Product Name	4-Pentenoicacid,2-Amino-5-Cyano-,Methylester,[S-(Z)]-(9Ci)
CAS No.	780725-65-7
Molecular Formula	C8H10N2O2
Molecular Weight	166.18 g/mol
Synonyms	(2S)-2-Amino-5-cyano-4-pentenoic acid methyl ester; (Z)-Methyl 2-amino-5-cyano-4-pentenoate; Methyl (2S,4Z)-2-amino-5-cyano-4-pentenoate; (S,Z)-Methyl 2-amino-5-cyano-4-pentenoate; 2-Amino-5-cyano-4-pentenoic acid methyl ester, (S)-(Z)-; (S)-Methyl 2-amino-5-cyano-(Z)-4-pentenoate; A chiral cyano-alkene amino ester
EINECS	Contact for details

Quality Control

Our 4-Pentenoicacid,2-Amino-5-Cyano-,Methylester,[S-(Z)]-(9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity (enantiomeric excess) and chemical purity assays, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing specific results for identity, purity, and impurities are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.