Description

3-(5-Bromopyridin-2-Yl)-1,1-Dimethyl-Prop-2-Ynylamine is a high-purity, advanced pharmaceutical intermediate featuring a bromopyridine core and a propargylamine moiety. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs), particularly for neurological and oncological targets.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially kinase inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of new pesticides and herbicides due to its heterocyclic structure.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalysis and material science.
• Chemical Biology Probes: Employed in the design of molecular probes for studying enzyme function and cellular pathways.
• Academic & Contract Research: Essential for organic synthesis and methodology development in university and CRO laboratories.

Basic Information

Product Name	3-(5-Bromopyridin-2-Yl)-1,1-Dimethyl-Prop-2-Ynylamine
CAS No.	778646-98-3
Molecular Formula	C10H11BrN2
Molecular Weight	239.11 g/mol
Synonyms	1,1-Dimethyl-3-(5-bromo-2-pyridinyl)-2-propyn-1-amine; N,N-Dimethyl-1-(5-bromopyridin-2-yl)prop-2-yn-1-amine; 2-[(Dimethylamino)methyl]-5-bromophenylacetylene; 5-Bromo-2-[(3-dimethylamino)prop-1-ynyl]pyridine; 778646-98-3; 3-(5-Bromo-2-pyridinyl)-N,N-dimethyl-2-propyn-1-amine
EINECS	Contact for details

Quality Control

Our 3-(5-Bromopyridin-2-Yl)-1,1-Dimethyl-Prop-2-Ynylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance in GMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.