Description

4-[4-(Benzyloxy)Phenyl]-1,2,3,6-Tetrahydropyridine is a high-purity advanced pharmaceutical intermediate with the CAS number 778642-53-8. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), valued for its specific structural framework. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within central nervous system (CNS) and other specialty drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Drug Discovery Research: Used as a core scaffold or building block in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• CNS-Active Compound Synthesis: Particularly relevant in the synthesis pathway for potential therapeutics targeting neurological and psychiatric disorders.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Employed in university and institutional labs for methodological development and pharmacological studies.
• Process Chemistry Development: Serves as a standard for scaling up synthetic routes from laboratory to pilot and commercial production.

Basic Information

Product Name	4-[4-(Benzyloxy)Phenyl]-1,2,3,6-Tetrahydropyridine
CAS No.	778642-53-8
Molecular Formula	C18H19NO
Molecular Weight	265.35 g/mol
Synonyms	4-(4-Benzyloxyphenyl)-1,2,3,6-tetrahydropyridine; 1,2,3,6-Tetrahydro-4-[4-(phenylmethoxy)phenyl]pyridine; 4-(4-(Benzyloxy)phenyl)-1,2,3,6-tetrahydropyridine; BZOP-THP; 778642-53-8 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized and controlled using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for all critical parameters are available upon request. Our quality management system supports development under cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.