Description

(2-Oxo-2-p-Tolyl-Ethyl)-Carbamic Acid tert-Butyl Ester is a high-purity, protected amino acid derivative widely used as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise molecular architecture, particularly in the development of complex active pharmaceutical ingredients (APIs). It serves as a key intermediate for pharmaceutical, agrochemical, and specialty chemical industries, enabling the synthesis of novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly for protease inhibitors and other small molecule therapeutics.
• Peptidomimetics Research: Used in medicinal chemistry for the design and construction of peptide analogs and peptidomimetics to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a key intermediate in the production of advanced herbicides, fungicides, and plant growth regulators.
• Custom Chemical Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring protected amino acid derivatives.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands and organocatalysts for asymmetric synthesis.
• Academic & Industrial R&D: A valuable reagent for exploratory chemistry in university and corporate research laboratories focusing on heterocyclic and fine chemical synthesis.

Basic Information

Item	Detail
Product Name	(2-Oxo-2-p-Tolyl-Ethyl)-Carbamic Acid tert-Butyl Ester
CAS No.	778617-65-5
Molecular Formula	C14H19NO3
Molecular Weight	249.31 g/mol
Synonyms	N-Boc-2-amino-1-(4-methylphenyl)ethanone; tert-Butyl (2-oxo-2-(p-tolyl)ethyl)carbamate; Boc-2-amino-4'-methylacetophenone; 2-((tert-Butoxycarbonyl)amino)-1-(4-methylphenyl)ethan-1-one; N-(tert-Butoxycarbonyl)-2-amino-4'-methylacetophenone; 2-(Boc-amino)-1-(p-tolyl)ethanone; (2-Oxo-2-(4-methylphenyl)ethyl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Every batch of (2-Oxo-2-p-Tolyl-Ethyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent batch-to-batch quality suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.