Description

5-Bromo-2-Chloro-4-Picoline is a halogenated pyridine derivative, a versatile and high-value chemical intermediate prized for its unique reactivity. Its molecular structure makes it a critical building block for synthesizing complex molecules in advanced research and development. This compound is essential for pharmaceutical chemists, agrochemical researchers, and material scientists developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the halogenated pyridine core provides specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of advanced organic electronic materials, such as components for organic light-emitting diodes (OLEDs) or conductive polymers.
• Chemical Biology & Proteomics: Utilized as a reactive handle for bioconjugation and the development of chemical probes for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	5-Bromo-2-Chloro-4-Picoline
CAS No.	778611-64-6
Molecular Formula	C6H5BrClN
Molecular Weight	206.47 g/mol
Synonyms	2-Chloro-5-bromo-4-methylpyridine; 4-Methyl-2-chloro-5-bromopyridine; 5-Bromo-2-chloro-4-methylpyridine; 2-Chloro-5-bromo-4-picoline; 4-Picoline, 5-bromo-2-chloro-; 5-Bromo-2-chloro-γ-picoline
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-Chloro-4-Picoline is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the exacting standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.