Description

2-Oxa-8-Azaspiro[4.5]Decan-6-Ol, (5R,6R)-Rel- (9Ci) is a high-purity, stereochemically defined spirocyclic compound that serves as a critical chiral building block in advanced organic synthesis. Its unique fused heterocyclic structure makes it a valuable intermediate for constructing complex molecules with precise three-dimensional architecture. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the creation of novel, stereoselective pesticides and herbicides where specific spatial orientation is crucial for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic & Industrial R&D: Employed in methodological studies and the synthesis of complex natural product analogs and molecular probes.
• Fine Chemical Production: Integral to the multi-step synthesis of high-value, specialty chemicals for electronics and material science applications.

Basic Information

Product Name	2-Oxa-8-Azaspiro[4.5]Decan-6-Ol, (5R,6R)-Rel- (9Ci)
CAS No.	778567-44-5
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	rel-(5R,6R)-2-Oxa-8-azaspiro[4.5]decan-6-ol; (5R,6R)-2-Oxa-8-azaspiro[4.5]decan-6-ol; 2-Oxa-8-azaspiro[4.5]decan-6-ol, (5R,6R)-rel-; Spirocyclic amino alcohol derivative; (5R,6R)-rel-2-Oxa-8-azaspiro[4.5]decan-6-ol; CAS 778567-44-5
EINECS	Contact for details

Quality Control

Our 2-Oxa-8-Azaspiro[4.5]Decan-6-Ol, (5R,6R)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider maintaining the product under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.