Description

3,4-Pyrrolidinediol,2-[(1R)-1-Hydroxyethyl]-,(2S,3S,4R)-(9Ci) is a high-purity, stereochemically defined pyrrolidine derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its precise stereochemistry and functional group array make it invaluable for constructing complex molecular architectures with high enantiomeric purity. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands and organocatalysts.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemical configurations.
• Academic & Industrial Research: A valuable tool for methodological development in organic chemistry and for studying structure-activity relationships (SAR).

Basic Information

Product Name	3,4-Pyrrolidinediol,2-[(1R)-1-Hydroxyethyl]-,(2S,3S,4R)-(9Ci)
CAS No.	778561-25-4
Molecular Formula	C6H13NO3
Molecular Weight	147.17 g/mol
Synonyms	(2S,3S,4R)-2-[(1R)-1-Hydroxyethyl]-3,4-pyrrolidinediol; (2S,3S,4R)-2-[(1R)-1-Hydroxyethyl]pyrrolidine-3,4-diol; 1-Deoxy-1-[(1R)-1-hydroxyethyl]-D-ribitol (related to aminocyclitol family); Chiral Pyrrolidinediol Derivative; (2S,3S,4R,1'R)-1'-Hydroxyethylpyrrolidine-3,4-diol; Stereoisomer of ABT-546 intermediate (related compound); Polyhydroxylated Pyrrolidine
EINECS	Contact for details

Quality Control

Every batch of 3,4-Pyrrolidinediol,2-[(1R)-1-Hydroxyethyl]-,(2S,3S,4R)-(9Ci) is produced under a strict quality management system to ensure identity, purity, and stereochemical integrity. Our products undergo rigorous quality testing, including chiral HPLC and NMR analysis, to ensure compliance with exacting research and development standards. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and all analytical results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.