Description

2-Piperidineacetic Acid, 5-Hydroxy-, (2R-Trans)- (9Ci) is a chiral piperidine derivative of significant interest in advanced organic synthesis. This compound serves as a crucial chiral building block and intermediate for the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with specific stereochemistry. The product is supplied with a high level of purity and batch-to-batch consistency to support critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and production of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Asymmetric Synthesis: Utilized as a building block in stereoselective synthesis to introduce the (2R-trans) configuration into complex molecular architectures.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in enantioselective transformations.
• Agrochemical Research: Intermediate in the development of new pesticides and herbicides where specific stereochemistry impacts biological activity.
• Academic & Industrial R&D: Used in chemical research to explore new reaction pathways and synthesize libraries of compounds for biological screening.
• Fine Chemical Production: Employed in the custom synthesis of high-value, specialty chemicals for various technological applications.

Basic Information

Product Name	2-Piperidineacetic Acid, 5-Hydroxy-, (2R-Trans)- (9Ci)
CAS No.	778553-70-1
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	(2R-trans)-5-Hydroxy-2-piperidineacetic Acid; 5-Hydroxypipecolic Acid Derivative; (2R,5R)-5-Hydroxypipecolic Acid; 2-Piperidineacetic acid, 5-hydroxy-, (2R-trans)-; (2R,5R)-5-Hydroxy-2-piperidinecarboxylic Acid (related structure); 5-Hydroxy-D-pipecolic Acid Analog; Chiral Hydroxylated Pipecolate
EINECS	Contact for details

Quality Control

Our 2-Piperidineacetic Acid, 5-Hydroxy-, (2R-Trans)- (9Ci) is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.