Description

2-Propanone, 1-Chloro-1-(4-Pyridinyl)- is a specialized halogenated ketone derivative that serves as a valuable synthetic intermediate in advanced organic chemistry. Its core value lies in its unique molecular scaffold, which combines a reactive α-chloroketone moiety with a 4-pyridinyl group, enabling its use in the construction of complex heterocyclic systems and active pharmaceutical ingredients (APIs). This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity building blocks for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those containing pyridine or piperidine heterocycles.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers.
• Academic & R&D Laboratories: A crucial reagent for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	2-Propanone, 1-Chloro-1-(4-Pyridinyl)-
CAS No.	778532-97-1
Molecular Formula	C8H8ClNO
Molecular Weight	169.61 g/mol
Synonyms	1-Chloro-1-(4-pyridinyl)acetone; 1-(4-Pyridinyl)-1-chloro-2-propanone; 4-Pyridyl Chloromethyl Ketone; α-Chloro-4-pyridylacetone; 1-Chloro-1-(pyridin-4-yl)propan-2-one; 4-Acetonylpyridinium Chloride (precursor form); 4-(2-Oxopropyl)pyridinium Chloride
EINECS	Contact for details

Quality Control

Our 2-Propanone, 1-Chloro-1-(4-Pyridinyl)- is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry for comprehensive characterization and purity verification. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.