Description

2-Piperidineacetic Acid, 3,4,5-Trihydroxy-, Ethyl Ester, [2S-(2Alpha,3Ba,4Ba,5Ba)]- (9Ci) is a high-purity, stereochemically defined piperidine derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated chiral building block, enabling the construction of complex molecular architectures with precise stereochemical control. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by academic institutions conducting studies in medicinal chemistry and chemical biology.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry Research: Used as a scaffold or precursor for constructing libraries of compounds in structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Employed in the development of advanced, stereospecific pesticides and herbicides.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes to study enzyme mechanisms and biological pathways.
• Asymmetric Catalysis Ligand Precursor: Acts as a starting material for the synthesis of novel chiral ligands used in asymmetric synthesis.
• Academic & Institutional R&D: A valuable reagent for university laboratories and research institutes exploring new synthetic methodologies and bioactive molecules.

Basic Information

Product Name	2-Piperidineacetic Acid, 3,4,5-Trihydroxy-, Ethyl Ester, [2S-(2Alpha,3Ba,4Ba,5Ba)]- (9Ci)
CAS No.	776274-24-9
Molecular Formula	C9H17NO5
Molecular Weight	219.24 g/mol
Synonyms	Ethyl (2S,3R,4R,5R)-3,4,5-trihydroxypiperidine-2-acetate; (2S,3R,4R,5R)-Ethyl 3,4,5-trihydroxy-2-piperidineacetate; 3,4,5-Trihydroxy-2-piperidineacetic acid ethyl ester (stereoisomer); 776274-24-9; A stereoisomer of Ethyl Swainsonine precursor; Polyhydroxylated piperidine ethyl ester
EINECS	Contact for details

Quality Control

Our 2-Piperidineacetic Acid, 3,4,5-Trihydroxy-, Ethyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.