Description

2,5-Pyridinediamine,3,4,5,6-Tetrahydro-4-Methyl-,(4R,5S)-Rel-(9Ci) is a high-purity, stereochemically defined chiral diamine derivative of tetrahydropyridine, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block in asymmetric synthesis. Its value lies in the precise stereochemistry and functional groups that enable the construction of complex molecules with high enantiomeric purity, essential for developing active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel therapeutic agents and high-value chiral compounds.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Asymmetric Synthesis: Utilized as a chiral ligand or auxiliary in catalytic asymmetric reactions to induce stereoselectivity.
• Agrochemical Development: Serves as a precursor in the creation of enantiomerically pure pesticides and herbicides.
• Fine Chemical Synthesis: Employed in the production of complex, high-value specialty chemicals requiring specific stereochemistry.
• Academic & Industrial Research: Used in methodological development and exploration of new reaction pathways in organic chemistry.
• Ligand for Metal Complexes: Can be used to prepare chiral metal complexes for catalysis.

Basic Information

Item	Details
Product Name	2,5-Pyridinediamine,3,4,5,6-Tetrahydro-4-Methyl-,(4R,5S)-Rel-(9Ci)
CAS No.	776270-44-1
Molecular Formula	C6H13N3
Molecular Weight	127.19 g/mol
Synonyms	(4R,5S)-4-Methyl-3,4,5,6-tetrahydro-2,5-pyridinediamine; rel-(4R,5S)-4-Methyl-1,2,3,6-tetrahydropyridine-2,5-diamine; 2,5-Diamino-4-methyl-1,2,3,6-tetrahydropyridine; 4-Methyl-3,4,5,6-tetrahydro-2,5-pyridinediamine (rel-(4R,5S)-form); Chiral Tetrahydropyridine Diamine; (4R,5S)-rel-4-Methyl-2,5-diamino-3,4,5,6-tetrahydropyridine
EINECS	Contact for details

Quality Control

Our production of 2,5-Pyridinediamine,3,4,5,6-Tetrahydro-4-Methyl-,(4R,5S)-Rel-(9Ci) adheres to stringent quality protocols suitable for pharmaceutical R&D and fine chemical synthesis. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (ee) and chemical purity. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.