Description

D-Proline, 4-Hydroxy-, Methyl Ester, (4S)-Rel- (9Ci) is a high-purity, non-proteinogenic amino acid derivative with a defined stereochemistry. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the construction of complex molecules with precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), peptide mimetics, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs) and therapeutic peptides.
• Peptidomimetics Research: Used to synthesize constrained peptide analogs and peptidomimetics for drug discovery programs targeting various diseases.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective organic reactions to induce desired chirality in target molecules.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and as a standard in analytical method development for amino acid analysis.
• Agrochemical Development: Potential use as an intermediate in the synthesis of chiral agrochemicals with specific biological activity.
• Material Science: Can be incorporated into specialty polymers or functional materials requiring specific molecular recognition properties.

Basic Information

Product Name	D-Proline, 4-Hydroxy-, Methyl Ester, (4S)-Rel- (9Ci)
CAS No.	775275-31-5
Molecular Formula	C6H9NO3
Molecular Weight	143.14 g/mol
Synonyms	(4S)-4-Hydroxy-D-proline methyl ester; Methyl (4S)-4-hydroxy-D-prolinate; Methyl (4R)-4-hydroxy-D-prolinate (rel); (2S,4S)-4-Hydroxypyrrolidine-2-carboxylic acid methyl ester; D-4-Hydroxyproline methyl ester; 4-Hydroxy-D-proline methyl ester; (4S)-4-Hydroxy-D-proline methyl ester; 775275-31-5
EINECS	Contact for details

Quality Control

Our D-Proline, 4-Hydroxy-, Methyl Ester, (4S)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and identity confirmation via IR and NMR. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.