Description

4-{5H,6H,7H,8H,9H-[1,2,4]Triazolo[4,3-A][1,3]Diazepin-3-Yl}Pyridine is a high-purity, advanced pharmaceutical intermediate featuring a fused triazolodiazepine-pyridine heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, particularly those targeting neurological pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• CNS Drug Development: Used in the R&D of potential therapeutics for conditions such as anxiety, sleep disorders, and epilepsy, leveraging its diazepine core.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in API production.

Basic Information

Product Name	4-{5H,6H,7H,8H,9H-[1,2,4]Triazolo[4,3-A][1,3]Diazepin-3-Yl}Pyridine
CAS No.	775260-07-6
Molecular Formula	C13H13N5
Molecular Weight	239.28 g/mol
Synonyms	4-(5H,6H,7H,8H,9H-[1,2,4]Triazolo[4,3-a][1,3]diazepin-3-yl)pyridine; 4-([1,2,4]Triazolo[4,3-a][1,3]diazepin-3-yl)pyridine; 775260-07-6; Pyridine, 4-[5H,6H,7H,8H,9H-[1,2,4]triazolo[4,3-a][1,3]diazepin-3-yl]-; 4-(5,6,7,8,9-Tetrahydro-[1,2,4]triazolo[4,3-a][1,3]diazepin-3-yl)pyridine
EINECS	Contact for details

Quality Control

Our 4-{5H,6H,7H,8H,9H-[1,2,4]Triazolo[4,3-A][1,3]Diazepin-3-Yl}Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.