Description

Spiro[2.4]Heptane-5-Carboxylic Acid, 6-Amino-, (5R,6S)- (9Ci) is a high-value, stereochemically defined spirocyclic building block of significant interest in advanced organic synthesis. Its unique rigid, three-dimensional structure makes it a critical intermediate for constructing complex molecular architectures with precise spatial orientation. This compound is primarily sought after by pharmaceutical and agrochemical research organizations for the development of novel active ingredients, where its scaffold can impart improved metabolic stability and target selectivity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in creating novel pesticides and herbicides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a precursor for sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with unique properties.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	Spiro[2.4]Heptane-5-Carboxylic Acid, 6-Amino-, (5R,6S)- (9Ci)
CAS No.	774535-21-6
Molecular Formula	C8H11NO2
Molecular Weight	153.18 g/mol
Synonyms	(5R,6S)-6-Aminospiro[2.4]heptane-5-carboxylic acid; (5R,6S)-6-Amino-1,4-dioxaspiro[2.4]heptane-5-carboxylic acid (related protected form); 6-Amino-spiro[2.4]heptane-5-carboxylic acid; (5R,6S)-Aminospiroheptanecarboxylic acid; Spirocyclic β-amino acid; SC-774535-21-6; (5R,6S)-6-Azaniumylspiro[2.4]heptane-5-carboxylate
EINECS	Contact for details

Quality Control

Every batch of Spiro[2.4]Heptane-5-Carboxylic Acid, 6-Amino-, (5R,6S)- (9Ci) is manufactured under strict quality management systems. We provide comprehensive analytical documentation to support your regulatory and R&D needs. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are supplied with each shipment. Our standard quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake, which can affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (5R,6S)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.