Description

Cyclohexanecarboxylic Acid, 3-Amino-, Methyl Ester, (1R,3S)-Rel-(-)- (9Ci) is a chiral, non-racemic intermediate of significant importance in asymmetric synthesis. Its defined stereochemistry at the 1 and 3 positions makes it a valuable building block for constructing complex molecules with high enantiomeric purity. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel therapeutic agents, particularly for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Research: Used in the development of enantiomerically pure pesticides and herbicides, where specific stereochemistry can be critical for bioactivity and environmental safety.
• Asymmetric Catalysis: Serves as a precursor or ligand for chiral catalysts used in stereoselective chemical transformations.
• Fine Chemical Synthesis: Employed in the production of specialty chemicals, flavors, and fragrances requiring precise stereocontrol.
• Academic & R&D: A valuable compound for methodological studies in organic chemistry and for exploring new synthetic pathways in laboratory settings.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 3-Amino-, Methyl Ester, (1R,3S)-Rel-(-)- (9Ci)
CAS No.	774523-44-3
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	(1R,3S)-(-)-3-Aminocyclohexanecarboxylic Acid Methyl Ester; Methyl (1R,3S)-(-)-3-Aminocyclohexanecarboxylate; rel-(1R,3S)-3-Aminocyclohexanecarboxylic Acid Methyl Ester; (-)-Methyl 3-aminocyclohexanecarboxylate (1R,3S); 3-Amino-1-cyclohexanecarboxylic Acid Methyl Ester, (1R,3S)-rel-(-)-; Chiral 3-Aminocyclohexanecarboxylate Ester
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric excess (e.e.). Quality is verified through advanced analytical techniques including Chiral HPLC and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.