Description

Bicyclo[2.2.2]Octane-1-Carboxylic Acid, 4-(Methylamino)-, Methyl Ester (9Ci) is a high-purity, synthetically valuable bicyclic organic compound featuring a rigid, three-dimensional scaffold. This unique structure makes it a critical advanced pharmaceutical intermediate and a versatile building block for sophisticated organic synthesis. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon or a rigid core structure in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its bicyclic framework can contribute to unique biological activity and stability.
• Ligand and Catalyst Development: Acts as a precursor for designing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed as a monomer or cross-linking agent in the synthesis of polymers with specific thermal or mechanical properties due to its rigid geometry.
• Academic & Industrial R&D: A valuable tool compound for methodological studies in organic chemistry, including cycloaddition reactions and stereoselective transformations.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex fragrance molecules, dyes, and other specialty chemicals.

Basic Information

Product Name	Bicyclo[2.2.2]Octane-1-Carboxylic Acid, 4-(Methylamino)-, Methyl Ester (9Ci)
CAS No.	774487-83-1
Molecular Formula	C11H19NO2
Molecular Weight	197.27 g/mol
Synonyms	Methyl 4-(methylamino)bicyclo[2.2.2]octane-1-carboxylate; 4-(Methylamino)bicyclo[2.2.2]octane-1-carboxylic acid methyl ester; Bicyclo[2.2.2]octane-1-carboxylic acid, 4-(methylamino)-, methyl ester; 1-Carbomethoxy-4-(methylamino)bicyclo[2.2.2]octane
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for this high-value intermediate. Production follows current Good Manufacturing Practice (cGMP) principles where applicable, and every batch is analyzed to meet exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically by HPLC), and impurity profiles is provided with each shipment to ensure traceability and compliance for your regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.