Description

Ethyl 2-Amino-4-Methyl-3-Oxopentanoate is a high-purity, non-proteinogenic amino acid ester derivative. This compound serves as a versatile and critical building block (synthon) in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs) and specialized biochemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly peptidomimetics and enzyme inhibitors.
• Peptide Synthesis: Used as a protected amino acid derivative in solid-phase and solution-phase peptide chemistry to introduce specific structural features.
• Agrochemical Research: Building block for developing new active ingredients with potential herbicidal or insecticidal properties.
• Biochemical Probe Development: Intermediate for creating labeled compounds or molecular probes used in biological and metabolic studies.
• Asymmetric Synthesis: Chiral synthon for the construction of enantiomerically pure compounds in medicinal chemistry.
• Academic & Industrial R&D: Essential reagent for research in organic methodology development and complex natural product synthesis.

Basic Information

Item	Details
Product Name	Ethyl 2-Amino-4-Methyl-3-Oxopentanoate
CAS No.	774477-26-8
Molecular Formula	C8H15NO3
Molecular Weight	173.21 g/mol
Synonyms	Ethyl 2-Amino-4-Methyl-3-Oxovalerate; 2-Amino-4-Methyl-3-Oxopentanoic Acid Ethyl Ester; Ethyl 2-Amino-4-Methyl-3-Oxo-pentanoate; Ethyl 2-Amino-4-methyl-3-oxopentanoate; 2-Azanyl-4-methyl-3-oxo-pentanoic acid ethyl ester; Amino Acid Ester Derivative; 774477-26-8; L- or D- forms may be specified.
EINECS	Contact for details

Quality Control

Our Ethyl 2-Amino-4-Methyl-3-Oxopentanoate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis where applicable, to ensure it meets precise customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (if applicable)	≥ 99.0% ee (Contact for specific isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.