Description

Carbamic Acid, (1-Cyano-2,2-Dimethylpropyl)-, 1,1-Dimethylethyl Ester (9Ci) is a specialized carbamate derivative featuring a cyano and tert-butyl ester group, serving as a valuable protected intermediate in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring high-purity building blocks for constructing complex molecules with precise stereochemistry. It is primarily utilized in the development of active pharmaceutical ingredients (APIs), agrochemicals, and sophisticated fine chemicals where its unique structure enables key transformations.

Application

• Pharmaceutical Intermediate: A key protected synthon in the multi-step synthesis of novel drug candidates, particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used as a building block for developing advanced pesticides and herbicides with specific modes of action.
• Peptidomimetics & Protease Inhibitors: The carbamate and cyano functional groups make it suitable for constructing peptide analogs and enzyme inhibitor scaffolds.
• Material Science Research: Serves as a monomer or precursor in the synthesis of specialized polymers and functional materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-fidelity intermediates.

Basic Information

Product Name	Carbamic Acid, (1-Cyano-2,2-Dimethylpropyl)-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	774225-53-5
Molecular Formula	C11H20N2O2
Molecular Weight	212.29 g/mol
Synonyms	tert-Butyl (1-cyano-2,2-dimethylpropyl)carbamate; N-(tert-Butoxycarbonyl)-3,3-dimethyl-4-aminobutyronitrile; Boc-ADMN; (1-Cyano-2,2-dimethylpropyl)carbamic acid tert-butyl ester; 3,3-Dimethyl-4-[(tert-butoxycarbonyl)amino]butyronitrile; 4-[(tert-Butoxycarbonyl)amino]-3,3-dimethylbutyronitrile; BOC-3-amino-3-methylbutyronitrile; 774225-53-5
EINECS	Contact for details

Quality Control

Our Carbamic Acid, (1-Cyano-2,2-Dimethylpropyl)-, 1,1-Dimethylethyl Ester (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements or regulatory standards for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.