Description

Methyl 5-Bromo-2-(Trifluoromethoxy)Benzoate is a high-purity, synthetically valuable organic building block. This compound is a key intermediate in the development of advanced pharmaceuticals and agrochemicals, particularly for molecules requiring a substituted benzoate core with halogen and trifluoromethoxy functionalities. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antiviral compounds.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the bromine and trifluoromethoxy groups contribute to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and organic synthesis methodologies.
• Material Science Research: Employed in the development of advanced organic materials, such as liquid crystals and polymers with specific electronic or optical properties.
• Custom Synthesis and Contract Manufacturing: A standard item for fine chemical suppliers and CDMOs (Contract Development and Manufacturing Organizations) offering bespoke synthesis services.

Basic Information

Product Name	Methyl 5-Bromo-2-(Trifluoromethoxy)Benzoate
CAS No.	773874-13-8
Molecular Formula	C9H6BrF3O3
Molecular Weight	299.04 g/mol
Synonyms	5-Bromo-2-(trifluoromethoxy)benzoic acid methyl ester; Methyl 5-bromo-2-(trifluoromethoxy)benzoate; Benzoic acid, 5-bromo-2-(trifluoromethoxy)-, methyl ester; 2-(Trifluoromethoxy)-5-bromobenzoic acid methyl ester; Methyl 5-bromo-α,α,α-trifluoro-o-anisate
EINECS	Contact for details

Quality Control

Our Methyl 5-Bromo-2-(Trifluoromethoxy)Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.