Description

3-Chloro-4-(Trifluoromethoxy)Methylbenzoate is a high-value fluorinated aromatic building block, essential for introducing the trifluoromethoxy (OCF₃) pharmacophore into advanced molecular architectures. This compound matters for its role in modulating the lipophilicity, metabolic stability, and binding affinity of target molecules, which is critical for developing new active ingredients. It is primarily needed by R&D and process chemists in the pharmaceutical and agrochemical industries for the synthesis of novel drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in CNS, oncology, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethoxy group enhances biological activity.
• Material Science Research: Serves as a precursor for specialty monomers and polymers, contributing to materials with unique surface properties and chemical resistance.
• Liquid Crystal & OLED Development: Employed in the synthesis of fluorinated components for electronic display materials and organic light-emitting diodes.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services to global clients.

Basic Information

Product Name	3-Chloro-4-(Trifluoromethoxy)Methylbenzoate
CAS No.	773874-04-7
Molecular Formula	C₁₀H₈ClF₃O₃
Molecular Weight	268.62 g/mol
Synonyms	Methyl 3-Chloro-4-(trifluoromethoxy)benzoate; Benzoic acid, 3-chloro-4-(trifluoromethoxy)-, methyl ester; 3-Chloro-4-trifluoromethoxybenzoic acid methyl ester; Methyl 3-chloro-α,α,α-trifluoro-p-anisate; 773874-04-7; Methyl 3-chloro-4-(trifluoromethoxy)benzoate
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-4-(Trifluoromethoxy)Methylbenzoate adheres to stringent quality management protocols. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification results is provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor quality specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.