Description

(R)-2-Amino-3-(2-Naphthyl)Propionicacidethylester is a chiral, non-natural amino acid derivative of significant synthetic utility. This compound serves as a crucial chiral building block and intermediate in advanced organic synthesis, particularly for the construction of complex molecules with defined stereochemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and other fine chemicals where stereochemical purity is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, including enzyme inhibitors and receptor modulators.
• Peptidomimetics & Bioactive Peptides: Used to incorporate a naphthylalanine derivative into peptide chains to enhance lipophilicity, stability, and receptor binding affinity.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective reactions to create enantiomerically pure compounds.
• Chemical Biology & Proteomics: Useful as a building block for synthesizing probes, labeled compounds, and molecular tools for studying biological systems.
• Material Science Research: Potential monomer or precursor for designing novel chiral polymers or organic frameworks with specific optical properties.
• Academic & Industrial R&D: Serves as a high-value reference standard and reagent in method development and discovery chemistry.

Basic Information

Product Name	(R)-2-Amino-3-(2-Naphthyl)Propionicacidethylester
CAS No.	773841-83-1
Molecular Formula	C₁₆H₁₉NO₂
Molecular Weight	257.33 g/mol
Synonyms	(R)-2-Amino-3-(naphthalen-2-yl)propanoic acid ethyl ester; Ethyl (R)-2-amino-3-(2-naphthyl)propionate; (R)-2-Naphthylalanine ethyl ester; D-2-Naphthylalanine ethyl ester; (R)-3-(2-Naphthyl)alanine ethyl ester; (R)-β-(2-Naphthyl)-L-alanine ethyl ester; (2R)-2-Amino-3-(naphthalen-2-yl)propanoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our production of (R)-2-Amino-3-(2-Naphthyl)Propionicacidethylester adheres to stringent quality protocols to ensure high chemical and enantiomeric purity suitable for research and development applications. Each batch is characterized by advanced analytical techniques, including chiral HPLC, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing assay, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.