Description

Ethyl 2-Fluoro-6-(Trifluoromethyl)Benzoate is a high-purity fluorinated aromatic ester building block of significant importance in advanced organic synthesis. Its value lies in the strategic placement of fluorine and trifluoromethyl groups, which are critical for modulating the physicochemical and biological properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to introduce these valuable fluorinated motifs into novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infective agents.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance metabolic stability and bioavailability.
• Liquid Crystal & OLED Materials: Used in the synthesis of fluorinated components for electronic display materials, leveraging its aromatic core and fluorine substituents to fine-tune electronic properties.
• Advanced Polymer Chemistry: Acts as a monomer or modifier in the production of specialty polymers with enhanced chemical resistance, thermal stability, and unique surface properties.
• Chemical Research & Development: Employed as a versatile building block in academic and industrial R&D for exploring new reactions and creating compound libraries for screening.

Basic Information

Product Name	Ethyl 2-Fluoro-6-(Trifluoromethyl)Benzoate
CAS No.	773134-93-3
Molecular Formula	C10H8F4O2
Molecular Weight	236.16 g/mol
Synonyms	Ethyl 2-Fluoro-α,α,α-trifluoro-o-toluate; 2-Fluoro-6-(trifluoromethyl)benzoic Acid Ethyl Ester; Benzoic acid, 2-fluoro-6-(trifluoromethyl)-, ethyl ester; Ethyl 2-fluoro-α,α,α-trifluoro-o-toluate; o-Toluic acid, 2-fluoro-α,α,α-trifluoro-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Fluoro-6-(Trifluoromethyl)Benzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles and relevant ICH guidelines ensures material integrity for demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider using an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.