Description

Methyl 5-Bromo-3-Fluoro-2-Hydroxybenzoate is a high-purity, multi-functional aromatic ester building block designed for advanced organic synthesis. This compound is valued for its precise molecular architecture, incorporating bromo, fluoro, and hydroxy substituents on a benzoate core, which enables selective derivatization and the construction of complex target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Serves as a versatile precursor for constructing advanced herbicides, fungicides, and pesticides, leveraging the bioactivity-modifying properties of the halogen and hydroxy groups.
• Material Science Research: Used in the synthesis of specialty monomers and ligands for advanced polymers, liquid crystals, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed as a building block for creating fluorescent tags, photoaffinity labels, and other molecular tools for biochemical research.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global fine chemical market.

Basic Information

Product Name	Methyl 5-Bromo-3-Fluoro-2-Hydroxybenzoate
CAS No.	773134-37-5
Molecular Formula	C8H6BrFO3
Molecular Weight	249.04 g/mol
Synonyms	5-Bromo-3-fluoro-2-hydroxybenzoic acid methyl ester; Methyl 5-bromo-3-fluoro-2-hydroxybenzoate; 2-Hydroxy-5-bromo-3-fluorobenzoic acid methyl ester; Benzoic acid, 5-bromo-3-fluoro-2-hydroxy-, methyl ester; Methyl 2-hydroxy-5-bromo-3-fluorobenzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 5-Bromo-3-Fluoro-2-Hydroxybenzoate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All material is characterized using advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.