Description

(6-(2,2,2-Trifluoroethoxy)Pyridin-3-Yl)Methanamine is a high-purity, advanced pharmaceutical intermediate featuring a pyridine core substituted with a trifluoroethoxy group and an aminomethyl functionality. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring fluorine-containing motifs. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in oncology, CNS, and antiviral therapies.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides where the trifluoroethoxy group enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands in catalytic systems and metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: Essential for academic and industrial research exploring the effects of fluorine substitution on molecular properties.
• Material Science: Potential building block for specialty polymers and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and scaled-up API synthesis.

Basic Information

Product Name	(6-(2,2,2-Trifluoroethoxy)Pyridin-3-Yl)Methanamine
CAS No.	771584-26-0
Molecular Formula	C8H9F3N2O
Molecular Weight	206.17 g/mol
Synonyms	1-[6-(2,2,2-Trifluoroethoxy)pyridin-3-yl]methanamine; 3-Pyridinemethanamine, 6-(2,2,2-trifluoroethoxy)-; (6-(2,2,2-Trifluoroethoxy)-3-pyridinyl)methanamine; 5-(Aminomethyl)-2-(2,2,2-trifluoroethoxy)pyridine; 2-(2,2,2-Trifluoroethoxy)-5-(aminomethyl)pyridine; 771584-26-0; 6-(2,2,2-Trifluoroethoxy)pyridin-3-ylmethylamine
EINECS	Contact for details

Quality Control

Our (6-(2,2,2-Trifluoroethoxy)Pyridin-3-Yl)Methanamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.