Description

(2,6-Dichloro-5-Fluoropyridin-3-Yl)Methanamine is a high-purity, multi-halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique halogen substitution pattern, which provides distinct reactivity for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine and chlorine atoms enhance biological activity and environmental stability.
• Material Science Research: Employed as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Acts as a versatile scaffold for designing molecular probes, enzyme inhibitors, and labeling reagents due to its reactive amine group.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up processes.

Basic Information

Product Name	(2,6-Dichloro-5-Fluoropyridin-3-Yl)Methanamine
CAS No.	771581-97-6
Molecular Formula	C6H5Cl2FN2
Molecular Weight	195.02 g/mol
Synonyms	3-(Aminomethyl)-2,6-dichloro-5-fluoropyridine; 5-Fluoro-2,6-dichloro-3-pyridinemethanamine; (2,6-Dichloro-5-fluoro-3-pyridinyl)methanamine; 2,6-Dichloro-5-fluoro-3-(aminomethyl)pyridine; 771581-97-6; 3-Pyridinemethanamine, 2,6-dichloro-5-fluoro-; (5-Fluoro-2,6-dichloro-pyridin-3-yl)-methylamine
EINECS	Contact for details

Quality Control

Our (2,6-Dichloro-5-Fluoropyridin-3-Yl)Methanamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each shipment, supporting compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.