Description

3-Pyridinemethanamine, 2-(2,2,2-Trifluoroethoxy)- is a specialized heterocyclic amine building block featuring a trifluoroethoxy substituent, which imparts unique electronic and physicochemical properties. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the development of new drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoroethoxy group can enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Useful for designing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses serving the life sciences industry.

Basic Information

Item	Details
Product Name	3-Pyridinemethanamine, 2-(2,2,2-Trifluoroethoxy)-
CAS No.	771581-20-5
Molecular Formula	C8H9F3N2O
Molecular Weight	206.17 g/mol
Synonyms	2-(2,2,2-Trifluoroethoxy)-3-pyridinemethanamine; 2-(Trifluoroethoxymethyl)pyridin-3-amine; 3-Aminomethyl-2-(2,2,2-trifluoroethoxy)pyridine; (2-(2,2,2-Trifluoroethoxy)pyridin-3-yl)methanamine; 771581-20-5; 2-(Trifluoroethoxy)-3-(aminomethyl)pyridine; 3-(Aminomethyl)-2-(2,2,2-trifluoroethoxy)pyridine
EINECS	Contact for details

Quality Control

Our 3-Pyridinemethanamine, 2-(2,2,2-Trifluoroethoxy)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.