Description

3-Chloro-4-(1-Piperidin-4-Ylmethyl-Piperidin-4-Yloxy)Benzonitrile is a high-value, complex organic intermediate featuring a benzonitrile core substituted with a chloro group and a piperidinylmethyl-piperidinyloxy moiety. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical agents, particularly those targeting central nervous system (CNS) disorders. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic molecules, where precise chemical architecture is paramount for biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially for neurological and psychiatric applications.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel receptor targets.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold in the multi-step synthesis of complex APIs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Biochemical Tool Compound: May be utilized in vitro to study specific biological pathways and mechanisms of action.

Basic Information

Product Name	3-Chloro-4-(1-Piperidin-4-Ylmethyl-Piperidin-4-Yloxy)Benzonitrile
CAS No.	770741-07-6
Molecular Formula	C18H24ClN3O
Molecular Weight	333.86 g/mol
Synonyms	3-Chloro-4-[(1-piperidin-4-ylmethylpiperidin-4-yl)oxy]benzonitrile; 4-[(1-[(Piperidin-4-yl)methyl]piperidin-4-yl)oxy]-3-chlorobenzonitrile; Benzonitrile, 3-chloro-4-[[1-(4-piperidinylmethyl)-4-piperidinyl]oxy]-; 770741-07-6; 3-Chloro-4-(1-piperidin-4-ylmethylpiperidin-4-yloxy)benzonitrile
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-(1-Piperidin-4-Ylmethyl-Piperidin-4-Yloxy)Benzonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling. Certificates of Analysis (COA) detailing identity, purity, and related substances are provided and available upon request, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.