Description

L-Alanine, (1S)-1-Hydroxy-1-Methylpropyl Ester (9Ci) is a specialized chiral building block and ester derivative of the amino acid L-alanine. This compound is valued for its role in advanced organic synthesis, particularly in the development of pharmaceuticals and fine chemicals where stereochemical purity is critical. It serves as a key intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific chiral centers into complex molecules.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and production of active pharmaceutical ingredients (APIs), especially in protease inhibitors and other small molecule drugs.
• Peptide Mimetics & Prodrug Development: Used to modify peptide structures or create ester-based prodrugs to enhance bioavailability and metabolic stability.
• Asymmetric Synthesis Catalyst/ Ligand Precursor: Serves as a starting material for synthesizing chiral ligands and catalysts used in enantioselective reactions.
• Agrochemical Research: Employed in the development of novel, chiral herbicides, fungicides, and plant growth regulators.
• Fine Chemical Synthesis: A building block for creating complex, high-value specialty chemicals with specific optical activity requirements.
• Biochemical Research: Used in studies of enzyme mechanisms and metabolic pathways involving amino acid derivatives.

Basic Information

Product Name	L-Alanine, (1S)-1-Hydroxy-1-Methylpropyl Ester (9Ci)
CAS No.	770722-11-7
Molecular Formula	C7H15NO3
Molecular Weight	161.20 g/mol
Synonyms	L-Alanyl 1-hydroxy-1-methylpropyl ester; (2S)-2-Aminopropanoic acid (1S)-1-hydroxy-1-methylpropyl ester; Alanine, (1S)-1-hydroxy-1-methylpropyl ester, L-; 1-Methyl-1-hydroxypropyl L-alaninate; (S)-1-Hydroxy-1-methylpropyl (S)-2-aminopropanoate
EINECS	Contact for details

Quality Control

Our L-Alanine, (1S)-1-Hydroxy-1-Methylpropyl Ester (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and GMP manufacturing. A detailed Certificate of Analysis (COA) specifying identity, purity, enantiomeric excess, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.