Description

4-Bromo-2-(Methylthio)Pyridine is a versatile brominated heterocyclic building block of significant importance in modern synthetic chemistry. Its core value lies in its dual functionalization, featuring a reactive bromine atom and a methylthio group, which facilitates a wide range of cross-coupling and functional group transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate in the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing functionalized pyridine cores.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or molecular components for OLEDs.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to form complex biaryl and amine structures.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological systems and protein interactions.

Basic Information

Item	Details
Product Name	4-Bromo-2-(Methylthio)Pyridine
CAS No.	769163-30-6
Molecular Formula	C7H8BrNS
Molecular Weight	218.11 g/mol
Synonyms	2-(Methylthio)-4-bromopyridine; 4-Bromo-2-methylsulfanylpyridine; 4-Bromo-2-(methylmercapto)pyridine; 4-Bromo-2-methylthiopyridine; 2-Methylsulfanyl-4-bromopyridine; Pyridine, 4-bromo-2-(methylthio)-; 769163-30-6
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(Methylthio)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.