Description

tert-Butyl 2'-Oxo-2',4'-Dihydro-1'H-Spiro[Piperidine-4,3'-Quinoline]-1-Carboxylate is a high-value, advanced pharmaceutical intermediate featuring a complex spirocyclic and quinoline-based molecular architecture. This compound matters as a critical building block for medicinal chemists, enabling the synthesis of novel drug candidates with potential activity in central nervous system and other therapeutic areas. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new drug molecules, particularly those targeting neurological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its complex, multifunctional heterocyclic core.
• API Synthesis: Employed in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs), especially those containing spirocyclic and quinoline motifs.
• Chemical Biology Probes: Utilized in the development of specialized chemical probes for studying biological targets and mechanisms.
• Custom Synthesis & Contract Manufacturing: A vital component for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke synthesis services for client projects.
• Academic Research: Used in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	tert-Butyl 2'-Oxo-2',4'-Dihydro-1'H-Spiro[Piperidine-4,3'-Quinoline]-1-Carboxylate
CAS No.	769106-43-6
Molecular Formula	C18H22N2O3
Molecular Weight	314.38 g/mol
Synonyms	1-Boc-2'-oxo-1',2'-dihydrospiro[piperidine-4,3'-quinoline]; tert-Butyl 2-oxo-1,2-dihydrospiro[piperidine-4,3'-quinoline]-1-carboxylate; Spiro[piperidine-4,3'-quinoline]-1-carboxylic acid, 2',4'-dihydro-2'-oxo-1'H-, 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-2'-oxo-1',2'-dihydrospiro[piperidine-4,3'-quinoline]; Boc-protected spiroquinolinone piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 2'-Oxo-2',4'-Dihydro-1'H-Spiro[Piperidine-4,3'-Quinoline]-1-Carboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, supporting your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.