Description

3-(3-Pyridyl)-D-Alanine Methyl Ester is a high-purity, non-natural amino acid derivative featuring a pyridyl side chain. This compound is a critical chiral building block in advanced pharmaceutical research and development, offering precise stereochemical control for complex molecule synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and metabolic disorder therapies.
• Peptidomimetics & Constrained Peptide Design: Used to introduce rigidity and specific binding motifs into peptide backbones for enhanced stability and bioactivity.
• Ligand Synthesis for Catalysis: Serves as a precursor for chiral ligands used in asymmetric synthesis and homogeneous catalysis.
• Agrochemical Research: Employed in the development of novel, enantiomerically pure pesticides and herbicides.
• Biochemical Probe Development: Utilized to create labeled analogs and probes for studying enzyme mechanisms and receptor interactions.
• Academic & Institutional Research: A valuable reagent for synthetic organic chemistry and medicinal chemistry projects in university and government laboratories.

Basic Information

Product Name	3-(3-Pyridyl)-D-Alanine Methyl Ester
CAS No.	767268-80-4
Molecular Formula	C9H12N2O2
Molecular Weight	180.20 g/mol
Synonyms	D-3-(3-Pyridyl)alanine methyl ester; Methyl (R)-3-(pyridin-3-yl)alaninate; (R)-Methyl 3-(pyridin-3-yl)alaninate; (R)-2-Amino-3-(3-pyridyl)propionic acid methyl ester; 3-Pyridyl-D-alanine methyl ester; D-β-(3-Pyridyl)alanine methyl ester; Methyl D-3-(3-pyridinyl)alaninate
EINECS	Contact for details

Quality Control

Our 3-(3-Pyridyl)-D-Alanine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (D-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.