Description

2-Cyclopropylmethoxy-3-Iodo-Pyridine is a high-value, halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a cyclopropylmethoxy ether and an iodine substituent, makes it an essential intermediate for constructing complex molecules with specific steric and electronic properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the cyclopropyl and iodine groups contribute to biological activity.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the construction of molecular probes for studying enzyme function and biological pathways, leveraging the reactivity of the iodine atom for further functionalization.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Sonogashira) to form new carbon-carbon bonds.
• Material Science Precursor: Potential intermediate in the synthesis of organic electronic materials and liquid crystals.

Basic Information

Product Name	2-Cyclopropylmethoxy-3-Iodo-Pyridine
CAS No.	766557-62-4
Molecular Formula	C9H10INO
Molecular Weight	275.09 g/mol
Synonyms	3-Iodo-2-(cyclopropylmethoxy)pyridine; 2-(Cyclopropylmethoxy)-3-iodopyridine; 3-Iodo-2-cyclopropylmethoxypyridine; Pyridine, 3-iodo-2-(cyclopropylmethoxy)-; 766557-62-4; 2-Cyclopropylmethoxy-3-iodopyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Cyclopropylmethoxy-3-Iodo-Pyridine is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed results from HPLC, NMR, and GC-MS are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.