Description

n-(4-tert-Butylsulfanyl-Pyridin-3-Yl)-2,2-Dimethyl-Propionamide is a specialized organic compound featuring a pyridine core modified with tert-butylthio and pivalamide substituents, which are critical for its function as a high-value chemical intermediate. This compound matters for its role in facilitating complex molecular synthesis, offering a unique sterically hindered amide linkage and sulfur-based functionality that are essential for constructing advanced target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, process development, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological or metabolic disorders.
• Agrochemical Research: Used in the development of new pesticides or herbicides, leveraging its unique sulfur-containing pyridine structure.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalysis and material science.
• Chemical Biology Probes: Employed in the design of molecular probes for studying enzyme function or protein interactions.
• Process Chemistry: Utilized in route scouting and optimization for the scalable production of complex molecules.
• Custom Synthesis: A starting material for contract research organizations (CROs) and fine chemical manufacturers producing bespoke compounds for clients.

Basic Information

Product Name	n-(4-tert-Butylsulfanyl-Pyridin-3-Yl)-2,2-Dimethyl-Propionamide
CAS No.	766557-58-8
Molecular Formula	C14H22N2OS
Molecular Weight	266.40 g/mol
Synonyms	2,2-Dimethyl-N-[4-[(1,1-dimethylethyl)thio]-3-pyridinyl]propanamide; 4-(tert-Butylthio)-3-pivalamidopyridine; N-(4-(tert-Butylthio)pyridin-3-yl)pivalamide; Pivalic acid (4-tert-butylsulfanyl-pyridin-3-yl)-amide; 766557-58-8; tert-Butyl 3-(pivalamido)pyridin-4-yl sulfide
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of n-(4-tert-Butylsulfanyl-Pyridin-3-Yl)-2,2-Dimethyl-Propionamide is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request. We adhere to cGMP guidelines where applicable to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.