Description

3-Cyano-2-Hydroxy-5-Iodopyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring cyano, hydroxy, and iodo substituents, makes it a valuable precursor for constructing complex heterocyclic systems and pharmaceutical intermediates. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality raw materials for their development and production processes.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functional organic molecules for electronic materials and organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Utilized as a building block for creating molecular probes and tags due to its reactive iodo and cyano groups.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) for carbon-carbon bond formation.

Basic Information

Product Name	3-Cyano-2-Hydroxy-5-Iodopyridine
CAS No.	766515-33-7
Molecular Formula	C6H3IN2O
Molecular Weight	245.01 g/mol
Synonyms	5-Iodo-2-hydroxynicotinonitrile; 2-Hydroxy-5-iodopyridine-3-carbonitrile; 5-Iodo-2-oxo-1,2-dihydropyridine-3-carbonitrile; 3-Cyano-5-iodo-2-pyridinol; 5-Iodo-3-cyano-2-pyridone; 2-Hydroxy-5-iodo-3-cyanopyridine; 5-Iodo-2-hydroxypyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 3-Cyano-2-Hydroxy-5-Iodopyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to quality supports compliance with cGMP and ISO standards for research and commercial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; containers should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.