Description

Carbamic Acid, [(1R,2S)-2-Hydroxy-1-(Hydroxymethyl)Propyl]-, 1,1- is a specialized chiral carbamate derivative with significant utility in advanced organic synthesis. This compound is valued for its role as a key chiral building block or intermediate in the production of high-value, optically active pharmaceuticals and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and development of novel, enantiomerically pure herbicides, fungicides, and insecticides for enhanced efficacy and environmental profile.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the preparation of chiral ligands used in asymmetric hydrogenation and other stereoselective transformations.
• Peptidomimetics & Prodrug Design: Employed in medicinal chemistry for constructing peptide analogs and designing prodrugs to improve bioavailability and metabolic stability.
• Fine Chemical & Specialty Material Production: Acts as a building block for advanced materials, liquid crystals, and other high-performance chemicals requiring specific stereochemistry.

Basic Information

Product Name	Carbamic Acid, [(1R,2S)-2-Hydroxy-1-(Hydroxymethyl)Propyl]-, 1,1-
CAS No.	766514-03-8
Molecular Formula	C6H13NO4
Molecular Weight	163.17 g/mol
Synonyms	(1R,2S)-1-(Hydroxymethyl)-2-hydroxypropyl carbamate; (1R,2S)-2-Hydroxy-1-(hydroxymethyl)propyl carbamate; (1R,2S)-1,2-Dihydroxy-3-methylbutyl carbamate (isomeric); L-Threoninol carbamate derivative; (2S,3R)-3-Amino-2-methyl-1,3-butanediol carbamate; Carbamic acid, (1,2-dihydroxy-3-methylbutyl)-, (1R,2S)-rel-; A chiral threoninol-based carbamate
EINECS	Contact for details

Quality Control

Our Carbamic Acid, [(1R,2S)-2-Hydroxy-1-(Hydroxymethyl)Propyl]-, 1,1- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.